Treatment options for pityriasis rubra pilaris including biologic agents: a retrospective analysis from an academic medical center.
نویسندگان
چکیده
Treatment Options for Pityriasis Rubra Pilaris Including Biologic Agents: A Retrospective Analysis From anAcademicMedical Center Pityriasis rubra pilaris (PRP) is characterized by hyperkeratoticpapules,palmoplantarkeratoderma, andwidespreaderythema with islands of sparing. Treatment is challenging, and a standard therapeutic protocol doesnot exist. Given thepaucity of available therapeutic data,weassessed the clinical presentation of PRP and clinical response (CR) to therapy at 2 teaching hospitals in Boston, Massachusetts. In addition, we aimed to determine the role of systemic and biologic agents.
منابع مشابه
Systemic sclerosis in a patient with pityriasis rubra pilaris
Pityriasis rubra pilaris (PRP) is a rare, chronic erythematous squamous disorder of unknown etiology. It has been found in association with several autoimmune diseases, including thyroiditis, myositis, myasthenia gravis and vitiligo. Herein we report a case of systemic sclerosis in a patient with classic adult pityriasis rubra pilaris. A 38 year old woman with classic adult type 1 pityriasis ru...
متن کاملOral Alitretinoin for the Treatment of Recalcitrant Pityriasis Rubra Pilaris
Treatment of pityriasis rubra pilaris is still challenging. We here present a 74-year-old woman who had not experienced stable remission of her skin symptoms during prior treatments including topical and systemic corticosteroids, phototherapy, orally administered acitretin, cyclosporine, methotrexate and adalimumab. A therapy with oral alitretinoin was started and tolerated very well. After a f...
متن کاملPityriasis rubra pilaris: evolution of challenges in promising treatment options.
Pityriasis rubra pilaris is an uncommon inflammatory dermatosis that is well recognized across the globe. Erythroderma is a common presentation. A precise diagnosis of pityriasis rubra pilaris is based on morphologic features and is classified into 6 types: classic adult onset (type I), atypical adult (type II), classic juvenile (type III), circumscribed juvenile (type IV), atypical juvenile (t...
متن کاملSuccessful treatment of type II pityriasis rubra pilaris with secukinumab
IL: interleukin PRP: pityriasis rubra pilaris TNF: tumor necrosis factor INTRODUCTION Pityriasis rubra pilaris (PRP) is a heterogeneous inflammatory skin disease characterized by follicular papules, orange palmoplantar keratoderma, and erythematous scaly patches with islands of skin sparing. Type II PRP is a rare, severe, chronic form of PRP presenting atypical features including long disease d...
متن کاملManagement of refractory pityriasis rubra pilaris: challenges and solutions
Pityriasis rubra pilaris (PRP) is a rare chronic inflammatory papulosquamous skin disease. Its clinical presentation and evolution is very variable. The most frequent clinical features are follicular papules, progressing to yellow-orange erythroderma with round small areas of normal skin and the well-demarcated palmoplantar keratoderma. Actually, six different types of PRP have been described b...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- JAMA dermatology
دوره 150 1 شماره
صفحات -
تاریخ انتشار 2014